Test Details: Immunohistochemical testing is carried out on biopsy/resected tissue specimen. This testing helps to identify specific antigens (proteins) within tissue sections utilizing an antigen-specific antibody .Cytokeratin 7 is a type II cytokeratin expressed in the majority of ductal and glandular epithelium in addition to transitional epithelium of the urinary tract. Cytokeratin 7 is one of the main markers for the diagnosis of Adenocarcinomas of the lung, salivary glands, pancreas, biliary tract, breast, endometrium, transitional cell carcinoma, ovarian serous tumors,Thyroid carcinoma, papillary and chromophobe renal cell carcinoma,mesothelioma. It is normally expressed by epithelium of the upper gastrointestinal tract, salivary glands, biliary tract, pancreas, lung, female genital tract, renal collecting ducts, transitional epithelium, mesothelial cells, thyroid follicle cells, endothelial cells .