Test Details: Immunohistochemical testing is carried out on biopsy/resected tissue specimen. This testing helps to identify specific antigens (proteins) within tissue sections utilizing an antigen-specific antibody .Hepatocyte paraffin-1 (Hep Par-1) is a specific marker for liver tissue and hepatocellular tumours; however, it also labels small intestinal mucosa and small intestinal adenocarcinomas in addition to gastric and oesophageal intestinal metaplasia including Barrett’s mucosa. It is also expressed in Adrenal gland tumours, mucosal intestinal metaplasia and small intestinal adenocarcinoma, signet ring cell carcinoma, tumours with hepatoid differentiation, yolk sac tumour.