Test Details: Immunohistochemical testing is carried out on biopsy/resected tissue specimen. This testing helps to identify specific antigens (proteins) within tissue sections utilizing an antigen-specific antibody .Vimentin is a 57-kDa protein, a member of the type III family of intermediate filaments, expressed in all mesenchymal cells forming an important part of the cytoskeleton of these cells. Vimentin is expressed in mesenchymal tumours .The use of Vimentin as a single marker is of limited diagnostic value as the co-expression of Vimentin with other different cytokeratins has been demonstrated in many types of epithelial cells and tumours such as carcinomas of the lung, salivary glands, liver and biliary tract, thyroid gland, adrenal cortex, kidney, endometrium, gonads and meningioma.