Test Details: CD123 or interleukin-3 (IL-3) receptor α chain is expressed in a wide variety of hematologic malignancies such as AML, precursor B-ALL, hairy cell leukaemia, a subset of CLL with strong CD11c expression, and blastic plasmacytoid dendritic cell neoplasms. CD123 is important for diagnosis of blastic plasmacytic dendritic cell neoplasm (BPDCN).