Test Details: Immunohistochemical testing is carried out on biopsy/resected tissue specimen. This testing helps to identify specific antigens (proteins) within tissue sections utilizing an antigen-specific antibody .34betaE12 is a high molecular weight cytokeratin present in all squamous epithelium and their carcinomas. High molecular cytokeratin also includes cytokeratins 1, 5,6, 10 and 14. These antibody labels squamous, ductal and complex epithelia. Results aid in the classification of prostatic adenocarcinoma and in the classification of neoplastic tissue as carcinoma of epithelial origin.