Test Details: Beta-Thalassemia is an inherited single gene disorder caused by mutations in beta globin chains, responsible for haemoglobin production. Beta Thalassemia is caused by point mutation, deletion or insertion within the Beta globin gene. Individuals are tested for the five most common mutations IVS1-5(G-C), IVS1-1(G-T), FS41-42(-CTTT), FS8-9(+G) and 619 bp deletion and common hemoglobinopathies such as HbS, HbE and HbD by ARMS PCR method. Beta thal mutation in parents is indicative of high risk of beta thal major/minor in the fetus necessitating beta thal mutation analysis for prenatal diagnosis.