Test Details: Cystic fibrosis (CF), also known as mucoviscidosis, is a genetic disorder that affects mostly the lungs but also the pancreas, liver, kidneys and intestine. CF is caused by a mutation in the gene cystic fibrosis transmembrane conductance regulator (CFTR). This test detects the most rare 6 mutations, representing three different categories--missense (R31L, W1098R), nonsense (E1104X) and frameshift (441delA, 681delC, 1461ins4)--are located in exons 2, 4, 5, 9 and 17b of the gene and presumed to cause cystic fibrosis (CF) in patients.