Test Details: Urine protein /creatinine ratio measures the amount of protein in urine. This test is used in cases of risk of developing kidney or cardiovascular problem. It is usually done in patients suffering from type I and type II diabetes mellitus. Protein in urine is normally composed of a combination of plasma-derived proteins that have been filtered by glomeruli and have not been reabsorbed by the proximal tubules and proteins secreted by renal tubules or other accessory glands. Increased amounts of protein in the urine may be due to: Glomerular proteinuria: conditions like glomerulonephritis or nephrotic syndrome, Tubular proteinuria: Caused by incomplete tubular reabsorption of proteins (e.g. interstitial nephritis).