Test Details: Progesterone is a hormone that is made mainly by the ovaries, which are two glands in the female reproductive system that contain eggs. A progesterone test can help show whether low progesterone levels are causing female infertility or problems during pregnancy. The test may also help diagnose certain problems like Ectopic Pregnancy, Ovarian Cancer and certain disorders of the adrenal glands that may cause high levels of progesterone in both females and males.